Penalized logistic regression for detecting gene interactions
نویسندگان
چکیده
منابع مشابه
Penalized logistic regression for detecting gene interactions.
We propose using a variant of logistic regression (LR) with (L)_(2)-regularization to fit gene-gene and gene-environment interaction models. Studies have shown that many common diseases are influenced by interaction of certain genes. LR models with quadratic penalization not only correctly characterizes the influential genes along with their interaction structures but also yields additional ben...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2007
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxm010